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Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents
Table of Contents for Proceedings of the National Academy of Sciences. List of articles from both the latest and ahead of print issues.
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In This Issue
Proceedings of the National Academy of Sciences, Volume 122, Issue 2, January 2025. <br/>
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Modeling DNA methyltransferase function to predict epigenetic correlation patterns in healthy and cancer cells
Proceedings of the National Academy of Sciences, Volume 122, Issue 2, January 2025. <br/>SignificanceDNA methylation plays a fundamental role in regulating gene expression and maintaining genomic stability. Errors in methylation patterning result in impaired cellular function and abnormal gene expression, which leads to cancer, ...
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An RNase III–processed sRNA coordinates sialic acid metabolism of Salmonella enterica during gut colonization
Proceedings of the National Academy of Sciences, Volume 122, Issue 2, January 2025. <br/>SignificanceSalmonellarelies on specialized transcriptional networks to thrive in diverse nutritional environments encountered within hosts, necessitating coordinated responses to dynamic changes. This study uncovers a unique genetic cluster in...
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The ecdysone-induced bZIP transcription factor MafB establishes a positive feedback loop to enhance vitellogenesis and reproduction in the Aedes aegypti mosquito
Proceedings of the National Academy of Sciences, Volume 122, Issue 2, January 2025. <br/>SignificanceFemale mosquitoes that serve as disease vectors require vertebrate blood to produce eggs. InAedes aegypti, blood-feeding signals the brain to release neurohormones that trigger 20-hydroxyecdysone (20E) production. 20E is essential for ...
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The false evidence rate: An approach to frequentist error rate control conditioning on the observed P value
Proceedings of the National Academy of Sciences, Volume 122, Issue 2, January 2025. <br/>APvalue is conventionally interpreted either as a) the probability by chance of obtaining more extreme results than those observed or b) a tool for declaring significance at a prespecified level. Both approaches carry difficulties: b) does not allow ...